Acetyl Hexapeptide-8

    💚Very good

    Also known as: Argireline

    Cell-Communicating Ingredient
    Moisturizer/Humectant
    Peptide

    What it is

    A synthetic peptide composed of six amino acids. It is a neurotransmitter-inhibiting peptide designed to reduce the appearance of expression wrinkles.

    How it works

    Acetyl Hexapeptide-8 mimics the N-terminal end of the SNAP-25 protein and competes with it for a position in the SNARE complex. By destabilizing this complex, it attenuates the release of acetylcholine, a neurotransmitter that causes muscle contraction. This leads to a relaxation of facial muscles, reducing the depth of dynamic wrinkles.

    Pairs well with

    Other peptides, Hyaluronic Acid

    Formulation notes

    Effective concentration: 2% - 10%

    pH range: 3.0 - 7.0

    Stability: Stable in aqueous solutions.

    Safety

    Irritancy: 0

    Comedogenicity: 0

    Ratings

    Paula's Choice: Best

    INCIdecoder: goodie

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