Azelaic Acid
💚Very good
Anti-Acne Agent
What it is
A naturally occurring dicarboxylic acid found in grains like barley, wheat, and rye. It is a multi-functional ingredient effective for treating acne, rosacea, and hyperpigmentation.
How it works
Azelaic acid has several mechanisms: it is antibacterial against C. acnes; it normalizes the keratinization process in the follicle, preventing pore blockages; it has potent anti-inflammatory properties that reduce redness; and it inhibits the tyrosinase enzyme to reduce hyperpigmentation.
Formulation notes
Effective concentration: 10% (OTC) to 20% (Prescription)
pH range: 4.0 - 5.0
Stability: Stable, but can be difficult to formulate due to low solubility.
Safety
Irritancy: Low to moderate, can cause itching or burning initially.
Comedogenicity: 0
Ratings
Paula's Choice: Best
INCIdecoder: superstar